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MD® Intimate Restore — Clinical Evidence

MD® Intimate Restore

Clinical Evidence Dossier — Gynecologist-Developed, Hormone-Free Intimate Rejuvenation Serum

Overview

MD® Intimate Restore is a hormone-free, peptide-powered intimate rejuvenation serum developed by board-certified gynecologist Dr. Susan Lin, M.D., founder of La Canada Ventures, Inc. The formula combines stem cell–conditioned factors with collagen-boosting peptides to address vulvovaginal skin changes associated with aging, perimenopause, menopause, and postpartum recovery — without estrogen or other hormones.

This page summarizes the independent dermatological safety study (Medcin Instituto da Pele, Brazil, 2017) and the consumer-acceptance group study (GVI, Mexico) commissioned by the sponsor, La Canada Ventures, Inc.

Study #1: Dermatological Safety — Medcin Instituto da Pele (Brazil, 2017)

ProtocolEN16-0158-01
Study TypeDermatological Compatibility — Primary Dermal Irritation, Cumulative Dermal Irritation, Dermal Sensitization
Principal InvestigatorDr. Flávia A. S. Addor, MD, Dermatologist (CRM 66.293-SP)
Clinical Research CenterMedcin Instituto da Pele Ltda., Osasco, São Paulo, Brazil
SponsorLa Canada Ventures, Inc., San Mateo, CA
Period17 July 2017 – 24 August 2017
Ethics ApprovalResearch Ethics Committee, University of São Francisco (07 April 2017)
Quality StandardsGood Clinical Practices (GCP) + NBR ISO 9001:2008; ICDRG reading scale

Study Population

55 participants screened and included, age 18–70 years (avg. 53.5 years), Fitzpatrick skin types I–IV. 54 completed the full protocol (one withdrawal for non-study reasons). Population was predominantly female (52 of 55).

Methodology

Three-phase patch-test compatibility study conducted in maximized conditions per ICDRG (International Contact Dermatitis Research Group) protocol:

  • Phase 1 — Primary Dermal Irritation: Semi-occlusive patches applied to the back of each participant; 48-hour evaluation, with re-evaluation at 96 hours.
  • Phase 2 — Cumulative Dermal Irritation: Eight repeated applications over three weeks with patch evaluation at each visit.
  • Phase 3 — Dermal Sensitization: Re-challenge phase following completion of cumulative irritation to detect delayed allergic response.

Dermatological assessment performed at baseline and at the end of each phase by the Principal Investigator.

Results

0/55
Cutaneous reactions in Primary Dermal Irritation phase
0/54
Cutaneous reactions in Cumulative Dermal Irritation phase
0/54
Cutaneous reactions in Dermal Sensitization phase

Conclusion (verbatim from Principal Investigator)

“Under the conditions that the product was assessed and in the sample of participants studied: there was no observed Primary Dermal Irritation potential; there was no observed Cumulative Dermal Irritation potential; there was no observed Dermal Sensitization potential. According to the recommendation of the Guide for the Evaluation of Safety of Cosmetic Products (ANVISA, 2012 — 2nd Edition), the product may be declared Dermatologically Tested.”

— Dra. Flávia Addor, MD, Principal Investigator (CRM 66.293-SP); Patricia C. P. Bombarda, Research Manager (CRF 44.770); David de Sá Filho, Quality Assurance (CRQ 04402151). Report Rep_PATCH.003_EN16-0158-01, v01_28.AUG.2017.

Study #2: Consumer-Acceptance Group Study — GVI (Mexico)

SponsorLa Canada Ventures, Inc.
Conducted ByGVI, Mexico (gvi.com.mx)
Study DesignAnonymous qualitative survey; daily use of MD® Intimate Restore
Groups TestedThree target populations × 5 participants each

Target Populations

  • Group 1 — Postpartum Vaginal Birth: 25–35 years old, sexually active, daily use
  • Group 2 — Postpartum C-Section: 25–35 years old, sexually active, daily use
  • Group 3 — Menopause: 45–55 years old, sexually active or not, daily use

Intended Product Benefits Assessed

  • Moisturizes to reduce skin irritation
  • Nourishes to improve skin elasticity and texture
  • Enhances feminine erogenous sensitivity

Key Group 1 (Postpartum Vaginal Birth) Findings

  • 4 of 5 participants would recommend the product for daily use
  • 4 of 5 participants would recommend MD® Intimate Restore to a friend or relative “for sure,” with the fifth saying “possibly”
  • Of those who had used another intimate-care product before, 2 rated MD® Intimate Restore as “better” than the alternative; 1 as “same”

Note: Group study findings are consumer-acceptance survey data and are not a substitute for randomized controlled trial results. Reported here for transparency.

Physician Authority Behind MD® Intimate Restore

Dr. Susan Lin, M.D. is the physician founder and CEO of La Canada Ventures, Inc., creator of the MD® family of beauty and wellness brands. She is board-certified in Obstetrics and Gynecology and in Anti-Aging Medicine, with 35+ years of clinical practice. She authored the chapter “Feminine Rejuvenation” (Part 3.8, pp. 549–560) in Harry’s Cosmeticology, 9th Edition (Chemical Publishing Co., ISBN 978-0-8206-0179-3) — covering vulvar skin rejuvenation using novel stem cell cytokine topicals, the same scientific approach underlying MD® Intimate Restore.

Manufacturing & Regulatory

  • Manufactured in the USA in a GMP-compliant, FDA-registered facility
  • Sponsor: La Canada Ventures, Inc. (San Mateo, California) — a physician-founded, NMSDC MBE–certified (BA1137), WBENC WBE–certified (1702688), veteran-owned, federally registered (SAM.gov UEI GHQRVKN8GEG7) small business
  • Trademark: MD Intimate Restore is a trademark owned by La Canada Ventures, Inc.

Press Coverage — 2015 Launch Announcement

13-Outlet National Press Syndication (August 25, 2015)

The development of MD® Intimate Restore was announced via PR Newswire on August 25, 2015 (Story ID SF79402) and was syndicated to 13 national and regional outlets:

  • Boston.com / Boston Globe Finance
  • Chicago Business Journal
  • Los Angeles Business Journal
  • San Francisco Business Times
  • Washington Business Journal
  • New York Business Journal
  • NBC 12 (Richmond, VA)
  • ABC 13 / WSET (Lynchburg / Roanoke)
  • Fox 19 / WXIX Cincinnati
  • WAFB (CBS Baton Rouge)
  • 760 KFMB (CBS Radio San Diego)
  • Physician Family Media
  • Pharmaceutical-Technology
View full 13-outlet press syndication with direct links →

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